US genome sequencing priorities decided

US protected lands mismatch biodiversity priorities.

Because habitat loss is the main cause of extinction, where and how much society chooses to protect is vital for saving species. The United States is well positioned economically and politically to pursue habitat conservation should it be a societal goal. We assessed the US protected area portfolio with respect to biodiversity in the country. New synthesis maps for terrestrial vertebrates, fres...

Genome Sequencing

The concept of genome sequencing is quite simple. Break your genome up into many different small fragments, clone those fragments into a cloning vector, isolate many clones, and sequence each clone. All of the techniques used for sequencing are well established. These are the same techniques that scientists used for the past twenty years to characterize many different individual genes. Using th...

Whole Genome Sequencing: An Efficient Approach in Food Safety Management System

Examining priorities for a primate genome project.

Examining Priorities for a Primate Genome Project We agree with the premise of Edwin H. McConkey, Agit Varki, and cosignatories that "[a] primate genome project deserves high priority" in the U.S. biomedical research enterprise (Letters, 25 Aug., p. 1295), but we disagree with their selection of the chimpanzee as the focus for these efforts, and with the recommendation to commit resources to ge...

Comparing whole genome sequencing and exome sequencing

Introduction Next-generation DNA sequencing empowers scientists to identify genetic variations associated with human disease at higher resolution and greater sensitivity than previously possible. Two approaches are commonly employed -exome sequencing and whole genome sequencing. Exome sequencing targets protein-coding regions comprising approximately 1% of the human genome, while whole genome s...